Author
Northwestern UniversityORCID 0000-0001-7390-4121Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Zibo Zhao, Meenal Karunanidhi, Sarah R. Gold…·Ali Shilatifard
The paper identifies and characterizes FCD-11, a first-in-class COMPASS inhibitor that reduces tumor size and extends survival in breast cancer models.
Bin Zheng, Ruxuan Qiu, Sarah R. Gold…·Ali Shilatifard
This study shows BRD2 promotes transcriptional initiation via bromodomain-dependent binding to acetylated histones and recruits TFIID, while BRD4 mediates elongation through CDK9 recruitment.
Saeid Mohammad Parast, Simai Wang, Marta Iwanaszko…·Ali Shilatifard
The paper identifies ELOA-dependent mechanisms regulating transcription maturation and links them to cellular senescence and aging through RNA processing defects and growth arrest.