Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia
Mahmoud H. Abou Alaiwa, Brieanna M. Hilkin, Margaret P. Price, Nicholas D. Gansemer, Michael R. Rector, Mal R. Stroik, Linda S. Powers, Kristin M. Whitworth, Melissa Samuel, Akansha Jain, Lynda S. Ostedgaard, Sarah E. Ernst, Winter Philibert, Linda D. Boyken, Thomas O. Moninger, , David Anthony Stoltz
This paper develops a PCD pig model with DNAI1 mutations and characterizes its respiratory and sinus disease features, showing similarities to human PCD.
bioRxiv · May 22, 2024 · PreprintPhysiology