David Anthony Stoltz

This paper shows that in utero ivacaftor treatment rescues multiple organ defects in CFTR-G551D pigs, improving pancreatic, gallbladder, and vas deferens function.

This study shows that mucociliary clearance is impaired in small airways of cystic fibrosis pigs, with impaired clearance exacerbated by purinergic agonist stimulation.

This paper develops a PCD pig model with DNAI1 mutations and characterizes its respiratory and sinus disease features, showing similarities to human PCD.

The paper compares gene expression and function of airway cell types in small and large porcine airways, finding distinct transcriptomes and functional roles.