IF1 connects obesity and insulin resistance through mitochondrial reprogramming in association with ANT2
Y. Wang, Y. Guan, J. Zhang, X. Cao, S. Shen, G. Zhong, X. Xong, Y. Xu, X. Zhang, H. Wang, J. Ye
This study shows that reduced IF1 in obesity leads to mitochondrial reprogramming through ANT2 downregulation, improving insulin sensitivity despite increased body weight on a high-fat diet.
bioRxiv · Sep 24, 2020 · PreprintPhysiology