Author

Xiaojie Xu

Academy of Military Medical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Bei TaniD· 1 shared Chen‐Ying LiuiD· 1 shared Hao TangiD· 1 shared Hongquan ZhangiD· 1 shared Jing Zhang· 1 shared Jintao SheniD· 1 shared Jun ZhaniD· 1 shared Juping Sun· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

Bei TanORCID

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2 papers

Recent·Most cited

An orally administered peptide hydrogel disentangles immune-microbiota crosstalk for long-term ulcerative colitis therapy

Tianyu Li, Mengqian Shi, Jintao Shen, Peng Zhou, Yaxuan Chen, Lu Yu, Juping Sun, Hao Tang, Qingyang Zhou, Yimeng Du, Bei Tan, Xiaojie Xu, Ruirui Xing, Xuehai Yan

This paper develops an orally administered peptide hydrogel that disrupts immune-microbiota interactions to treat ulcerative colitis, showing improved mucosal integrity and microbiota rebalancing in mice.

bioRxiv · Aug 24, 2026 · PreprintBioengineering

Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism

Weijie Wu, Miao Yu, Qianchen Li, Yiqian Zhao, Lei Zhang, Yi Sun, Zhenbin Wang, Yuqing Gong, Wenjing Wang, Chen‐Ying Liu, Jing Zhang, Yan Tang, Xiaojie Xu, Xiao-Jing Guo, Jun Zhan, Hongquan Zhang

This study identifies FRMD8 as a regulator of ER levels in ER-positive breast cancer, showing it confers tamoxifen resistance through dual mechanisms involving transcriptional and post-translational regulation of ER.

eLife · Mar 31, 2025Peer-reviewedCancer Biology