Author

Xijun Zhu

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Dominika Ewa Pieńkowska· 1 shared Jan GerhartziD· 1 shared Jianing ZhongiD· 1 shared Kha The NguyeniD· 1 shared Laura Donatella AttardiiD· 1 shared Mengxiong WangiD· 1 shared Nathanael S. GrayiD· 1 shared Nick A. PhillipsiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Dominika Ewa Pieńkowska

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1 paper

Recent·Most cited

Activating p53Y220C with a Mutant-Specific Small Molecule

Xijun Zhu, Woong Sub Byun, Dominika Ewa Pieńkowska, Kha The Nguyen, Mengxiong Wang, Sabin A. Nettles, Sai P. Gourisankar, Nick A. Phillips, Jan Gerhartz, Qixiang Geng, Tian Qiu, Jianing Zhong, Zixuan Jiang, Roman C. Sarott, Stephen M. Hinshaw, , Nathanael S. Gray

This paper develops a small molecule, TRAP-1, that activates mutant p53 by forming a ternary complex with BRD4, leading to p53 target gene upregulation and inhibition of cancer cell growth.

Nature Communications · May 2, 2026Peer-reviewedCancer Biology