Author

Xinfu Jiao

Rutgers, The State University of New Jersey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1

Frequent Co-Authors

Megerditch KiledjianiD· 4 shared Ronald P. HartiD· 3 shared Geeta PalsuleiD· 2 shared Huijuan CuiiD· 2 shared Alfonso RoqueiD· 1 shared Ewa Grudzien‐Nogalska· 1 shared Gabriella D’ArcangeloiD· 1 shared Ishan KhoslaiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

Megerditch KiledjianORCID

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Author profile →

4 papers

Recent·Most cited

Extracellular Exosomal RNAs are Glyco-Modified

Sunny Sharma, Xinfu Jiao, Jun Yang, Kelvin Y. Kwan, Megerditch Kiledjian

This study identifies glyco-modified RNAs in exosomes, showing their role in intercellular communication and suggesting a link between protein and RNA glycosylation.

Nature Cell Biology · Jun 1, 2025Peer-reviewedCell Biology

Defective DcpS Decapping Manifests in Creatine Deficiency Syndrome and Neurological impairment

Jun Yang, Geeta Palsule, Xinfu Jiao, Jaime S Messenger, Ronald P. Hart, Megerditch Kiledjian

This study identifies creatine deficiency as the underlying cause of neurogenesis defects in DcpS mutant cells and shows creatine supplementation reverses the phenotype.

Scientific Reports · May 23, 2025Peer-reviewedCell Biology

mRNA-decapping associated DcpS enzyme controls critical steps of neuronal development

Iva Salamon, Geeta Palsule, Xiaobing Luo, Alfonso Roque, Shawn Tucai, Ishan Khosla, Nicole L. Volk, Wendy J. Liu, Huijuan Cui, Valentina Dal Pozzo, Petronio D. Zalamea, Xinfu Jiao, Gabriella D’Arcangelo, Ronald P. Hart, Mladen‐Roko Rašin, Megerditch Kiledjian

This study shows that DcpS, an mRNA-decapping enzyme, is critical for neuronal development and that its mutation leads to developmental delay and intellectual disability.

Cerebral Cortex · Aug 3, 2021Peer-reviewedNeuroscience

Structural and biochemical studies define Nudt12 as a new class of RNA deNADding enzyme in mammalian cells

Ewa Grudzien‐Nogalska, Yixuan Wu, Xinfu Jiao, Huijuan Cui, Ronald P. Hart, Liang Tong, Megerditch Kiledjian

This study identifies Nudt12 as a new deNADding enzyme distinct from DXO, showing it targets NAD-capped RNAs and links these RNAs to cellular metabolism.

bioRxiv · Nov 20, 2018 · PreprintMolecular Biology