Author

Xingyu Ma

Purdue University West LafayettePrimary ORCID profile (0000-0001-5268-5169 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Xingyu MaiD1 paper · Tongji University

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Qingfei ZhengiD· 3 shared Anne A LeamaniD· 2 shared Huapeng LiiD· 2 shared Lin ZengiD· 2 shared Zhengjun Cai· 2 shared Adam R. Lovato· 1 shared Andrew SymasekiD· 1 shared Chongli YuaniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersBiochemistry

Qingfei ZhengORCID

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3 papers

Recent·Most cited

Transglutaminase 3 is a Histone Monoaminylation Writer

Yvonne Ritsema, H. Li, Xingyu Ma, Anne A Leaman, Qingfei Zheng

The paper identifies TG3 as a new histone monoaminylation writer capable of catalyzing H3Q5 histaminylation.

bioRxiv · Oct 21, 2026 · PreprintBiochemistry

Chemoselective Bioconjugation Reveals Norepinephrinylation (NEylation) as a Widespread Post-Translational Modification in Cells

Lin Zeng, Xingyu Ma, Zhengjun Cai, Yunpeng Bai, Q Wang, Huapeng Li, Andrew Symasek, Adam R. Lovato, Sydny Lyon, Yin Zhao, Fei Gao, Nathaniel W. Mabe, Chongli Yuan, Zhong‐Yin Zhang, Qingfei Zheng

The paper develops a chemoselective bioconjugation method to detect and analyze NEylation, revealing it as a widespread PTM affecting protein function in cells.

bioRxiv · Aug 10, 2026 · PreprintBiochemistry

Chemical Proteomic Profiling of the Histaminylation Proteome in Cancer Cells Unveils Uncharted Epigenetic Marks on Core Histones

Xingyu Ma, Anne A Leaman, Lin Zeng, Huapeng Li, Zhengjun Cai, Qianyue Wang, Kaiwaan Dalal, Md Shahadat Hossain, Venkatesh P. Thirumalaikumar, Zhihong Wang, Valerie P. O’Brien, W. Andy Tao, Qingfei Zheng

This study identifies new TGM2-catalyzed histaminylation marks on core histones in cancer cells and reveals their crosstalk with γH2AX formation in DNA damage responses.

Journal of the American Chemical Society · Aug 3, 2026Peer-reviewedBiochemistry