Author
Rice UniversityORCID 0000-0002-7212-9802Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Andrew R. Gilmour, Qiyao Wei, Jessica Hellinger, Devon L. Kulhanek, Zachary Jansen, Katelyn M. Baumer, Jennifer S. Brodbelt, Ross T Thyer
The paper develops a fluorescent reporter, SeARCh, to quantify selenocysteine incorporation and reports a hybrid biosynthetic pathway achieving 90% Sec incorporation.
bioRxiv · Aug 10, 2026 · PreprintSynthetic Biology
Devon L. Kulhanek, Qiyao Wei, Jared Cason Head, Jessica Hellinger, Zachary Jansen, Andrew R. Gilmour, Thomas H. Segall-Shapiro, Jennifer S. Brodbelt, Syed Muhammad Usama, Ross T Thyer
The paper identifies mutations in smURFP that significantly increase in vivo fluorescence in E. coli through deep mutational scanning and biophysical analysis.
Protein Science · May 6, 2026Peer-reviewedSynthetic Biology
Zachary Jansen, Xuan Le, Qiyao Wei, Devon L. Kulhanek, Nina Alperovich, Olga B Vasilyeva, Andrew R. Gilmour, David Ross, Ross T Thyer
The paper uses Deep Mutational Scanning and Growth-based Quantitative Sequencing to analyze CymR variants and identify amino acids essential for repressor function and mutations that improve ligand sensitivity.
Nucleic Acids Research · Feb 24, 2026Peer-reviewedSynthetic Biology
Zachary Jansen, Sophia R. Reilly, Matan Lieber-Kotz, Andrew Z. Li, Qiyao Wei, Devon L. Kulhanek, Andrew R. Gilmour, Ross T Thyer
The paper develops bicistronic translational control elements (BCDs) that provide consistent gene expression across diverse contexts and species.
ACS Synthetic Biology · May 30, 2023Peer-reviewedSynthetic Biology