Exploring the Antifibrotic Potential of the heparan sulfate mimetic OTR4120: Insights from Preclinical Models
Manuela Marega, Najet Mejdoubi‐Charef, David Wiegard, Muzamil Majid Khan, Marek Bartkuhn, Laura Gambs, Tara Procida‐Kowalski, Jochen Wilhelm, Esmeralda Vásquez‐Pacheco, Afshin Noori, Ying Dong, Yi Zheng, Xuran Chu, Arun Lingampally, Joanna Zukowska, , Savério Bellusci
This study evaluates the antifibrotic effects of OTR4120 in lung fibrosis models, showing reduced collagen deposition and fibroblast activation.
bioRxiv · Oct 17, 2024 · PreprintCell Biology