Author

Y Z Tian

Drexel University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Jason DaCunza· 2 shared Jason R. WickmaniD· 2 shared Seena K. AjitiD· 2 shared Ahmet SaçaniD· 1 shared Deepa ReddyiD· 1 shared Elias K. HaddadiD· 1 shared Ezgi KasimogluiD· 1 shared Richa PandeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Jason DaCunza

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2 papers

Recent·Most cited

Microglial epigenetic memory is associated with accelerated resolution of inflammatory pain induced by prophylactic macrophage-derived small extracellular vesicles

Xuan Luo, Jason R. Wickman, Jason DaCunza, Y Z Tian, Ahmet Saçan, Seena K. Ajit

The paper shows that macrophage-derived sEVs reduce inflammatory pain by reprogramming microglial epigenetic memory, specifically through H3K4me1 enrichment and SETD7 inhibition.

Journal of Inflammation Research · Jul 1, 2026Peer-reviewedNeuroscience

Macrophage-derived extracellular vesicles promote T cell-dependent inflammatory pain resolution

Jason R. Wickman, Richa Pande, Jason DaCunza, Deepa Reddy, Y Z Tian, Ezgi Kasimoglu, Roshell Muir, Elias K. Haddad, Seena K. Ajit

This study shows that macrophage-derived extracellular vesicles promote inflammatory pain resolution via T cell-dependent immune mechanisms in mice.

bioRxiv · Mar 5, 2026 · PreprintNeuroscience