Author

Jason R. Wickman

Drexel UniversityORCID 0000-0002-5693-8917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Jason DaCunza· 3 shared Seena K. AjitiD· 3 shared Ahmet SaçaniD· 2 shared Deepa ReddyiD· 2 shared Ezgi KasimogluiD· 2 shared Richa PandeiD· 2 shared Y Z Tian· 2 shared Cristina M. FurduiiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Jason DaCunza

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Microglial epigenetic memory is associated with accelerated resolution of inflammatory pain induced by prophylactic macrophage-derived small extracellular vesicles

Xuan Luo, Jason R. Wickman, Jason DaCunza, Y Z Tian, Ahmet Saçan, Seena K. Ajit

The paper shows that macrophage-derived sEVs reduce inflammatory pain by reprogramming microglial epigenetic memory, specifically through H3K4me1 enrichment and SETD7 inhibition.

Journal of Inflammation Research · Jul 1, 2026Peer-reviewedNeuroscience

Macrophage-derived extracellular vesicles promote T cell-dependent inflammatory pain resolution

Jason R. Wickman, Richa Pande, Jason DaCunza, Deepa Reddy, Y Z Tian, Ezgi Kasimoglu, Roshell Muir, Elias K. Haddad, Seena K. Ajit

This study shows that macrophage-derived extracellular vesicles promote inflammatory pain resolution via T cell-dependent immune mechanisms in mice.

bioRxiv · Mar 5, 2026 · PreprintNeuroscience

Inflammatory pain resolution by mouse serum-derived small extracellular vesicles

Zhucheng Lin, Xuan Luo, Jason R. Wickman, Deepa Reddy, Jason DaCunza, Richa Pande, Yuzhen Tian, Ezgi Kasimoglu, Vivian Triana, Jingyun Lee, Cristina M. Furdui, Desmond Pink, Ahmet Saçan, Seena K. Ajit

This study shows that mouse serum-derived small extracellular vesicles can reduce inflammatory pain through opioid signaling and immunomodulation.

Brain Behavior and Immunity · Sep 30, 2024Peer-reviewedNeuroscience