Structural Basis for Regulated Assembly of the Mitochondrial Fission GTPase Drp1
K. Rochon, B. L. Bauer, N. A. Roethler, Y. Buckley, C.-C. Su, W. Huang, R. Ramachandran, M. S. K. Stoll, E. W. Yu, D. J. Taylor, J. A. Mears
This paper presents a cryo-EM structure of Drp1 dimer revealing conformational rearrangements that regulate its self-assembly and mitochondrial fission.
bioRxiv · Jun 22, 2023Cell Biology