Y. G.-J. Sterckx

This study investigates the role of intrinsic disorder in invariant surface glycoproteins (ISGs) of African trypanosomes, showing they can switch between compact and elongated conformers to balance immune evasion and host interaction.

This study shows that Leishmania parasites enter quiescence after 4-6 divisions in hematopoietic stem cells, enabling drug resistance and increased infectivity.

This study experimentally selects resistance to a novel anti-leishmanial compound in Leishmania donovani and identifies mutations in the dynamin-1-like protein as a key mechanism of resistance.