Author

M. Jara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 3 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Approach:experimental assay· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J.-C. Dujardin· 4 shared M. A. Domagalska· 4 shared G. Machado· 3 shared H. Imamura· 3 shared I. Maes· 3 shared J. A. Cotton· 2 shared J. Arevalo· 2 shared M. Berriman· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersMicrobiology

J.-C. Dujardin

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Quantifying the genomic determinants of fitness in E. coli ST131 using phylodynamics

L. M. Kepler, M. Jara, B. Mahmud, G. Dantas, E. Dubberke, C. Lanzas, D. A. Rasmussen

This study quantifies the genomic determinants of fitness in E. coli ST131 using phylodynamic models, finding that fluoroquinolone resistance mutations provide a major fitness advantage.

bioRxiv · Jun 10, 2024 · PreprintEvolutionary Biology

Unveiling drug tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis

M. Jara, J. Arevalo, A. Llanos-Cuentas, F. Van den Broeck, M. A. Domagalska, J.-C. Dujardin

The paper demonstrates drug tolerance in Leishmania braziliensis strains through in vitro models, showing quiescence and reversibility without genetic resistance.

bioRxiv · Jul 4, 2023 · PreprintMicrobiology

Genomic and phenotypic characterization of experimentally selected resistant Leishmania donovani reveals a role for dynamin-1 like protein in the mechanism of resistance to a novel anti-leishmanial compound

A. Hefnawy, G. Negreira, M. Jara, J. A. Cotton, I. Maes, E. D'Haenens, H. Imamura, B. Cuypers, P. Monsieurs, C. Mouchtoglou, H. De Winter, M. Berriman, M. Sanders, J. Martin, G. De Muylder, , M. A. Domagalska

This study experimentally selects resistance to a novel anti-leishmanial compound in Leishmania donovani and identifies mutations in the dynamin-1-like protein as a key mechanism of resistance.

bioRxiv · Jan 5, 2021Microbiology

Nairobi Sheep Disease Virus: a historical and epidemiological perspective

S. Krasteva, M. Jara, A. F.-D.-D. Frias-De-Diego, G. Machado

This study identifies regions at risk for Nairobi Sheep Disease virus (NSDv) circulation by analyzing environmental factors and literature data.

bioRxiv · Apr 13, 2020Ecology

Porcine reproductive and respiratory syndrome virus dissemination across pig production systems in the United States

M. Jara, D. Rasmussen, C. A. Corzo, G. Machado

This study investigates PRRSV dissemination across U.S. pig production systems, finding frequent cross-system transmission and highlighting geographic factors influencing spread.

bioRxiv · Apr 9, 2020Evolutionary Biology

Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level

H. Imamura, M. Jara, P. Monsieurs, M. Sanders, I. Maes, M. Vanaerschot, M. Berriman, J. A. Cotton, J.-C. Dujardin, M. A. Domagalska

The paper evaluates WGA methods for Leishmania single-cell genomics, finding PicoPlex better for aneuploidy and RepliG for SNPs, and detects aneuploidy mosaicism in L. braziliensis.

bioRxiv · Feb 20, 2020Microbiology

Tracking of quiescence in Leishmania by quantifying the expression of GFP in the ribosomal DNA locus

M. Jara, I. Maes, H. Imamura, M. A. Domagalska, J.-C. Dujardin, J. Arevalo

The paper develops a biosensor to track quiescence in Leishmania by quantifying GFP expression from the ribosomal DNA locus, showing it correlates with replication state and is reversible.

Scientific Reports · Dec 12, 2019Peer-reviewedMicrobiology

Phylogeography of equine infectious anemia virus

M. Jara, A. Frias-De-Diego, G. Machado

This study maps the global spread of EIAV using phylogeographic analysis and bibliometric review, identifying Hungary as the likely origin and highlighting research disparities.

bioRxiv · Dec 6, 2019Evolutionary Biology