Author

S. B. Peterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:bacteria (other)· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2

Frequent Co-Authors

J. D. Mougous· 6 shared M. C. Radey· 5 shared L. A. Gallagher· 4 shared Y. Wang· 4 shared H. E. Ledvina· 3 shared Y. Li· 3 shared C. A. Tower· 2 shared D. Baker· 2 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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6 shared papersMicrobiology

J. D. Mougous

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Essential and virulence-related protein interactions of pathogens revealed through deep learning

I. R. Humphreys, J. Zhang, M. Baek, Y. Wang, A. Krishnakumar, J. Pei, I. Anishchenko, C. A. Tower, B. A. Jackson, T. Warrier, D. T. Hung, S. B. Peterson, J. D. Mougous, Q. Cong, D. Baker

This study uses deep learning to predict protein-protein interactions in bacterial pathogens, identifying new complexes involving essential genes and virulence factors, with half of tested predictions validated.

bioRxiv · Apr 12, 2024 · PreprintBiochemistry

Umbrella toxin particles produced by Streptomyces block mycelial growth of competing species

Q. Zhao, S. Bertolli, Y.-J. Park, Y. Tan, K. J. Cutler, P. Srinivas, K. L. Asfahl, C. Fonseca Garcia, L. A. Gallagher, Y. Li, Y. Wang, D. Coleman-Derr, F. DiMaio, D. Zhang, S. B. Peterson, , J. D. Mougous

This study identifies umbrella toxin particles produced by Streptomyces that inhibit the growth of competing bacterial species, distinct from small molecule antibiotics.

bioRxiv · Dec 9, 2023 · PreprintMicrobiology

Genetic manipulation of candidate phyla radiation bacteria provides functional insights into microbial dark matter

Y. Wang, L. A. Gallagher, P. A. Andrade, A. Liu, I. R. Humphreys, S. Turkarslan, K. J. Cutler, M. L. Arrieta-Ortiz, Y. Li, M. C. Radey, J. S. McLean, Q. Cong, D. Baker, N. S. Baliga, S. B. Peterson, J. D. Mougous

The paper genetically manipulates Saccharibacteria from the CPR to study their role in epibiotic growth and develops bioinformatic resources for their analysis.

bioRxiv · May 2, 2023Microbiology

Discovery of a unique pathway for glutathione utilization in Francisella

Y. Wang, H. E. Ledvina, C. A. Tower, S. Kambarev, E. Liu, J. C. Charity, L. S. M. Kreuk, Q. Chen, L. A. Gallagher, M. C. Radey, G. F. Rerolle, Y. Li, K. M. Penewit, S. Turkarslan, S. J. Skerrett, , J. D. Mougous

This study identifies a unique GSH utilization pathway in Francisella, revealing a pseudogenized transporter gene in pathogenic strains and its role in environmental niches.

bioRxiv · Feb 2, 2023Microbiology

Coordinately regulated interbacterial antagonism defense pathways constitute a bacterial innate immune system

S.-Y. Ting, K. D. LaCourse, H. E. Ledvina, R. Zhang, M. C. Radey, H. D. Kulasekara, R. Somavanshi, S. K. Bertolli, L. A. Gallagher, J. Kim, K. M. Penewit, S. J. Salipante, L. Xu, S. B. Peterson, J. D. Mougous

This study identifies three conserved interbacterial antagonism resistance clusters in Pseudomonas aeruginosa that function independently and provide specific defense against phospholipase toxins.

bioRxiv · Aug 22, 2021Microbiology

An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations

M. H. de Moraes, F. Hsu, D. Huang, D. E. Bosch, J. Zeng, M. C. Radey, N. Simon, H. E. Ledvina, J. P. Frick, P. A. Wiggins, S. B. Peterson, J. D. Mougous

This study shows that interbacterial toxins like DddA can induce mutations in surviving bacterial populations, promoting adaptation through direct DNA mutagenesis.

bioRxiv · Sep 23, 2020Microbiology

Acquired interbacterial defense systems protect against interspecies antagonism in the human gut microbiome

B. D. Ross, A. J. Verster, M. C. Radey, D. T. Schmidtke, C. E. Pope, L. R. Hoffman, A. Hajjar, S. B. Peterson, E. Borenstein, J. Mougous

bioRxiv · Jul 11, 2019Microbiology

Introducing THOR, a model microbiome for genetic dissection of community behavior

G. L. Lozano, J. I. Bravo, M. F. Garavito Diago, H. B. Park, A. Hurley, S. B. Peterson, E. V. Stabb, J. M. Crawford, N. A. Broderick, J. Handelsman

The paper introduces THOR, a model rhizosphere microbiome composed of three dominant taxa, to study community behavior through genetic dissection and emergent properties.

bioRxiv · Dec 19, 2018Microbiology

OGT (O-GlcNAc Transferase) selectively modifies multiple residues unique to lamin A

D. N. Simon, A. Wriston, Q. Fan, J. Shabanowitz, A. Florwick, T. Dharmaraj, S. B. Peterson, Y. Gruenbaum, C. R. Carlson, L. M. Gronning-Wang, D. F. Hunt, K. L. Wilson

This study identifies O-GlcNAc modifications unique to lamin A, showing OGT modifies specific residues in lamin A tails but not lamin B1, lamin C, or progerin.

bioRxiv · Oct 26, 2017Biochemistry