Author

Y. K. Tai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1

Frequent Co-Authors

A. Franco-Obregon· 2 shared J. L. Y. Yap· 2 shared A. Othman· 1 shared A. P. F. Koh· 1 shared B. W. L. Tan· 1 shared B. W. Q. Tan· 1 shared B. Wollscheid· 1 shared C. Chai· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Franco-Obregon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modulated TRPC1 expression predicts sensitivity of breast cancer to doxorubicin and magnetic field therapy: segue towards a precision medicine approach.

Y. K. Tai, K. K. W. Chan, C. H. H. Fong, S. Ramanan, J. L. Y. Yap, J. N. Yin, Y. S. Yip, W. R. Tan, A. P. F. Koh, N. S. Tan, C. W. Chan, R. Y. J. Huang, A. Franco-Obregon

This study shows TRPC1 expression predicts breast cancer sensitivity to doxorubicin and PEMF therapy, suggesting TRPC1 as a biomarker for precision medicine approaches.

Frontiers in Oncology · Jan 24, 2022Peer-reviewedCancer Biology

mTOR S-nitrosylation inhibits autophagy and lysosomal proteolysis

B. W. Q. Tan, S. Tan, B. W. L. Tan, S. Navakkode, C. Y. Ng, S. Yuan, M. C. Liang, C. Liu, S. Yin, C. Chai, K. C. M. Chew, Y. K. Tai, S. Sreedharan, Y. Lam, P. Liao, , T. W. Soong

This study identifies mTOR S-nitrosylation as a kinase-independent mechanism that suppresses autophagy and lysosomal proteolysis, with implications for Alzheimer's disease.

bioRxiv · Sep 11, 2020 · PreprintCell Biology

Cell-Derived Vesicles as TRPC1 Channel Delivery Systems for the Recovery of Cellular Respiratory and Proliferative Capacities

F. Kurth, Y. K. Tai, D. Parate, M. van Oostrum, Y. R. F. Schmid, S. J. Toh, J. L. Y. Yap, B. Wollscheid, A. Othman, P. S. Dittrich, A. Franco-Obregon

This study shows that cell-derived vesicles from C2C12 myoblasts can restore mitochondrial function and proliferative capacity in recipient cells through TRPC1-mediated calcium entry.

bioRxiv · May 16, 2020Cell Biology