Author

S. Sreedharan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Laxman· 2 shared A. Prasad· 1 shared A. S. Walvekar· 1 shared B. Bakthavachalu· 1 shared B. W. L. Tan· 1 shared B. W. Q. Tan· 1 shared C. Chai· 1 shared C. Liu· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

S. Laxman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aedes aegypti eggs use rewired polyamine and lipid metabolism to survive extreme desiccation

A. Prasad, S. Sreedharan, B. Bakthavachalu, S. Laxman

This study identifies polyamine and lipid metabolism rewiring in Aedes aegypti eggs that enable survival of extreme desiccation and subsequent hatching.

bioRxiv · Dec 30, 2022 · PreprintBiochemistry

mTOR S-nitrosylation inhibits autophagy and lysosomal proteolysis

B. W. Q. Tan, S. Tan, B. W. L. Tan, S. Navakkode, C. Y. Ng, S. Yuan, M. C. Liang, C. Liu, S. Yin, C. Chai, K. C. M. Chew, Y. K. Tai, S. Sreedharan, Y. Lam, P. Liao, , T. W. Soong

This study identifies mTOR S-nitrosylation as a kinase-independent mechanism that suppresses autophagy and lysosomal proteolysis, with implications for Alzheimer's disease.

bioRxiv · Sep 11, 2020 · PreprintCell Biology

Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program

A. S. Walvekar, G. Kadamur, S. Sreedharan, R. Gupta, R. Srinivasan, S. Laxman

The paper identifies a methionine-induced mechanism where Ppm1-mediated PP2A methylation stabilizes Gcn4, enabling anabolic growth programs.

bioRxiv · May 5, 2020Biochemistry