Y. Komaru

Acute kidney injury triggers hypoxemia by inducing intravascular neutrophil retention that reduces lung capillary blood flow

This study identifies that acute kidney injury causes hypoxemia through intravascular neutrophil retention in lung capillaries, reducing blood flow without lung edema.

Acute kidney injury-induced circulating TNFR1/2 elevations correlate with persistent kidney injury and progression to fibrosis

This study shows that acute kidney injury (AKI) increases circulating TNFR1/2 levels, which correlate with kidney injury severity and progression to fibrosis, particularly through extracellular vesicle-bound forms.