M. J. Miller

Acute kidney injury triggers hypoxemia by inducing intravascular neutrophil retention that reduces lung capillary blood flow

This study identifies that acute kidney injury causes hypoxemia through intravascular neutrophil retention in lung capillaries, reducing blood flow without lung edema.

Microbial aromatic amino acid metabolism is modifiable in fermented food matrices to promote bioactivity

This study identifies aryl-lactates as bioactive metabolites in fermented foods and shows their production can be enhanced to boost AhR receptor activity.

Engineered Secretory Immunoglobulin A provides insights on antibody-based effector mechanisms targeting Clostridiodes difficile

This study engineers chimeric SIgA to investigate and enhance effector mechanisms against C. difficile, showing increased neutralization and bacterial clumping.

Honey varietals differentially impact Bifidobacterium animalis ssp lactis survivability in yogurt through simulated in vitro digestion

This study evaluates how different honey varietals and concentrations affect the survival of B. animalis in yogurt during in vitro digestion, finding that clover honey at 10-20% w/w significantly improves probiotic survivability.

An enhancer RNA recruits MLL1 to regulate transcription of Myb

The paper identifies Myrlin, an enhancer RNA that recruits MLL1 to regulate Myb transcription during erythroid differentiation.

Virion-associated US28 rapidly modulates Akt activity to suppress HCMV lytic replication in monocytes

This study shows virion-associated US28 modulates Akt activity to suppress HCMV lytic replication in monocytes, enabling quiescent infection.

Comparative phylogeography reveals widespread cryptic diversity driven by ecology in Panamanian birds

This study identifies cryptic diversity in Panamanian birds using mitochondrial DNA barcodes and finds ecological factors, not geography, drive speciation.

Time in allopatry does not predict the outcome of secondary contact in lowland Panamanian birds

The paper tests if time in allopatry predicts reproductive isolation in birds, finding ecological factors, not time, better predict hybridization outcomes.

Listeria motility increases the efficiency of goblet cell invasion during intestinal infection

This study shows that Listeria motility enhances goblet cell invasion during intestinal infection by improving target cell engagement and invasion efficiency.

GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis

This study shows GCN2 kinase supports prostate cancer growth by maintaining amino acid homeostasis, and a GCN2 inhibitor effectively reduces tumor growth in mouse models.

Prostaglandin E2 induction by cytosolic Listeria monocytogenes in phagocytes is necessary for optimal T-cell priming

This study identifies PGE2 production via COX-2 as a cytosol-dependent innate immune response critical for CD8+ T-cell priming against L. monocytogenes.

Proteomic fingerprint identification of Neotropical hard tick species (Acari: Ixodidae) using a self-curated mass spectra reference library

The paper identifies Neotropical hard tick species using MALDI mass spectra and machine learning, showing that self-curated reference libraries can replace commercial ones for accurate identification.

Phylogenomics clarifies biogeographic and evolutionary history, and conservation status of West Indian tremblers and thrashers (Aves: Mimidae)

This study uses ddRAD-seq to clarify the phylogenetic relationships and evolutionary history of West Indian thrashers and tremblers, revealing a monophyletic group and supporting the recognition of two distinct endemic species.