Author

Y. Kurachi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1

Frequent Co-Authors

K. Tsumoto· 2 shared A. Amano· 1 shared I.-S. Chen· 1 shared J. T. Sack· 1 shared K. Furutani· 1 shared K. Handa· 1 shared N. Naito· 1 shared T. Ashihara· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

K. Tsumoto

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2 papers

Recent·Most cited

Specific decreasing of Na+ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome

K. Tsumoto, T. Ashihara, N. Naito, T. Shimamoto, A. Amano, Y. Kurata, Y. Kurachi

This study shows that reduced Na+ channel expression in the lateral membrane of cardiomyocytes leads to phase-2 reentry, causing lethal arrhythmias in Brugada syndrome.

bioRxiv · Oct 16, 2019Biophysics

Facilitation of hERG channels by blockers: a mechanism predicted to reduce lethal cardiac arrhythmias

K. Furutani, K. Tsumoto, I.-S. Chen, K. Handa, Y. Yamakawa, J. T. Sack, Y. Kurachi

This paper proposes that hERG channel facilitation by blockers can reduce lethal cardiac arrhythmias by preventing early afterdepolarizations during repolarization.

bioRxiv · Jun 8, 2018Pharmacology & Toxicology