A mechanism to prevent transformation of the Whi3 mnemon into a prion.
Y. Lau, I. Parfenova, J. Saarikangas, R. A. Nichols, Y. Barral, F. Caudron
This study identifies how Whi3mnem, a memory-like protein in yeast, remains stable in mother cells but is not inherited by daughter cells through ER membrane anchoring and diffusion barriers.
bioRxiv · Mar 13, 2020 · PreprintCell Biology