Author

J. Saarikangas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:yeast· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

F. Caudron· 2 shared K. Tong· 2 shared Y. Barral· 2 shared A. J. Burnetti· 1 shared A. Krisko· 1 shared A. Lippi· 1 shared A. Nieminen· 1 shared D. Schnyder· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

F. Caudron

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Proteostatic tuning underpins the evolution of novel multicellular traits

K. Montrose, D. T. Lac, A. J. Burnetti, K. Tong, G. O. Bozdag, M. Hukkanen, W. C. Ratcliff, J. Saarikangas

The paper shows that downregulation of Hsp90 drives cellular elongation and multicellular adaptation in the MuLTEE experiment, revealing a proteostatic mechanism for macroscopic multicellularity evolution.

bioRxiv · May 31, 2023 · PreprintEvolutionary Biology

Global analysis of aging-related protein structural changes uncovers enzyme polymerization-based control of longevity

J. Paukstyte, R. M. Lopez Cabezas, Y. Feng, K. Tong, D. Schnyder, E. Elomaa, P. Gregorova, M. Doudin, M. Sarkka, J. Sarameri, A. Lippi, H. Vihinen, J. Juutila, A. Nieminen, P. Toronen, , J. Saarikangas

The paper identifies age-related protein structural changes in yeast and shows that inhibiting polymerization of glutamate synthase extends lifespan.

bioRxiv · Jan 23, 2023Cell Biology

A rare natural lipid induces neuroglobin expression to prevent amyloid oligomers toxicity and retinal neurodegeneration.

H. P. Oamen, N. Romero Romero, P. Knuckles, J. Saarikangas, Y. Dong, F. Caudron

The natural lipid tripentadecanoin induces neuroglobin expression to protect against amyloid oligomer toxicity and retinal neurodegeneration in mammals.

bioRxiv · Jun 23, 2021Cell Biology

A mechanism to prevent transformation of the Whi3 mnemon into a prion.

Y. Lau, I. Parfenova, J. Saarikangas, R. A. Nichols, Y. Barral, F. Caudron

This study identifies how Whi3mnem, a memory-like protein in yeast, remains stable in mother cells but is not inherited by daughter cells through ER membrane anchoring and diffusion barriers.

bioRxiv · Mar 13, 2020 · PreprintCell Biology