Y. Mao

TREEasy automates gene tree, species tree, and phylogenetic network inference from multilocus data, improving efficiency and reducing manual effort in evolutionary analysis.

This study evaluates the efficacy and adverse effects of antibiotics in treating M. abscessus pulmonary disease, finding that four antibiotics correlate with treatment success but are associated with severe side effects.

This study evaluates an IMU-based method for estimating foot trajectory and gait parameters, showing good accuracy compared to motion capture systems.

The paper shows that reducing junctional tension increases tissue fluidity, which accelerates wound healing in epithelial tissues.

The paper presents cryo-EM structures of the human 26S proteasome in seven conformational states during polyubiquitylated protein degradation, revealing dynamic substrate-proteasome interactions and ATP hydrolysis mechanisms.

The paper identifies an ancient whole-genome duplication in the coral genus Acropora, linked to its diversification and stress response mechanisms.

This study shows that isotropic tissue tension is necessary for proper mitotic spindle orientation in epithelial cells, with spindle alignment failing in low-tension regions.

The paper identifies a mechanosensitive pathway that uses Myosin II polarization to stiffen tissues and buffer mechanical stress, preventing damage and preserving tissue shape.

The paper develops a base-resolution m1A profiling method and identifies distinct m1A methylome classes in human nuclear and mitochondrial transcripts, showing functional roles in translation efficiency and mitochondrial mRNA regulation.

This study identifies three states of the ATP-gammaS-bound human proteasome, showing nucleotide-driven remodeling of the AAA-ATPase channel controls CP gate opening.

The paper determines the cryo-EM structure of the human proteasome regulatory particle bound to p28, revealing its dynamic conformational landscape and role in proteasome assembly.