Non-sedating benzodiazepines cause contractile paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni
P. McCusker, Y. Mian, G. Li, M. D. Olp, V. V. N. P. B. Tiruveedhula, F. Rashid, L. K. Golani, B. C. Smith, J. M. Cook, J. D. Chan
This study identifies non-sedating benzodiazepines that cause contractile paralysis and tissue damage in Schistosoma mansoni, offering potential for new anti-schistosomal drugs with reduced host side effects.
bioRxiv · Jul 8, 2019Pharmacology & Toxicology