Author

B. C. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. D. Olp· 2 shared A. Gupta· 1 shared A. K. Brown· 1 shared A. Lauth· 1 shared A. W. Orr· 1 shared B. C. Lega· 1 shared C. B. Dhaou· 1 shared D. D. Shi· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

M. D. Olp

Author profile →

6 papers

Recent·Most cited

Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway

J. Zhang, J. Chang, V. Chen, M. A. Beg, W. Huang, L. Vick, Y. Wang, H. Zhang, E. Yttre, A. Gupta, M. Castleberry, Z. Zhang, W. Dai, S. Song, J. Zhu, , Y. Chen

This study identifies the CD36-PKM2-mtROS pathway as a mechanism by which oxidized LDL disrupts efferocytosis, contributing to atherosclerosis progression.

bioRxiv · Sep 7, 2023 · PreprintImmunology

Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment

M. R. Savani, M. El Shami, L. C. Gattie, B. C. Smith, W. H. Hicks, S. S. Oken, L. G. Zacharias, M. S. Martin-Sandoval, E. Y. Montgomery, Y. Xiao, D. D. Shi, J. N. Rich, T. E. Richardson, P. O. Zinn, B. C. Lega, , K. G. Abdullah

This paper develops an in vitro method using human plasma-like medium to study glioma metabolism and immune interactions, revealing microenvironment-dependent metabolic features and immune responses.

bioRxiv · May 29, 2023Cancer Biology

NMR Resonance Assignment of the LA Motif of Human LA-Related Protein 1

B. C. Smith, R. Silvers

The paper presents a nearly complete NMR resonance assignment of the La motif in HsLARP1, facilitating future structural and functional studies.

bioRxiv · May 9, 2023Biophysics

Mitigation of Injury from Myocardial Infarction by TH1834, an Inhibitor of the Acetyltransferase Tip60

X. Wang, T. C. Wan, K. R. Kulik, A. Lauth, B. C. Smith, J. W. Lough, J. A. Auchampach

This study shows that inhibiting Tip60 acetyltransferase with TH1834 improves cardiac function and reduces damage after myocardial infarction in mice.

bioRxiv · Nov 9, 2021 · PreprintPharmacology & Toxicology

Nucleosome scaffolding by Brd4 tandem bromodomains in acetylation-dependent chromatin compartmentalization

M. D. Olp, V. Jackson, B. C. Smith

This study investigates how Brd4 tandem bromodomains scaffold acetylated nucleosomes, contributing to chromatin compartmentalization through cooperative binding mechanisms.

bioRxiv · Jul 11, 2019 · PreprintBiochemistry

Non-sedating benzodiazepines cause contractile paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni

P. McCusker, Y. Mian, G. Li, M. D. Olp, V. V. N. P. B. Tiruveedhula, F. Rashid, L. K. Golani, B. C. Smith, J. M. Cook, J. D. Chan

This study identifies non-sedating benzodiazepines that cause contractile paralysis and tissue damage in Schistosoma mansoni, offering potential for new anti-schistosomal drugs with reduced host side effects.

bioRxiv · Jul 8, 2019Pharmacology & Toxicology