Author

Y. N. Hou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:rat· 1

Frequent Co-Authors

F. J. Shen· 2 shared G. Z. Wu· 2 shared H. Zhang· 2 shared J. G. Su· 2 shared J. J. Wu· 2 shared J. W. Hou· 2 shared J. Zhang· 2 shared L. F. Du· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

F. J. Shen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants

J. Zhang, Z. B. Han, Y. Liang, X. F. Zhang, Y. Q. Jin, L. F. Du, S. Shao, H. Wang, J. W. Hou, K. Xu, Z. H. Lei, Z. M. Liu, J. Zhang, Y. N. Hou, N. Liu, , Q. M. Li

This study develops a mosaic-type trimeric RBD vaccine that induces strong neutralizing antibodies against Omicron and other SARS-CoV-2 variants in rats.

bioRxiv · Mar 29, 2022Immunology

Structure and computation-guided design of a mutation-integrated trimeric RBD candidate vaccine with broad neutralization against SARS-CoV-2

Y. Liang, J. Zhang, R. Y. Yuan, M. Y. Wang, P. He, J. G. Su, Z. B. Han, Y. Q. Jin, J. W. Hou, H. Zhang, X. F. Zhang, S. Shao, Y. N. Hou, Z. M. Liu, L. F. Du, , Q. M. Li

This paper designs a trimeric RBD vaccine candidate with mutations from multiple SARS-CoV-2 strains, showing broad neutralization against variants including Beta and Kappa.

bioRxiv · Jun 18, 2021 · PreprintImmunology

Permeant Fluorescent Probes Visualize the Activation of SARM1 and Uncover an Anti-neurodegenerative Drug Candidate

W. H. Li, K. Huang, Y. Cai, Q. W. Wang, W. J. Zhu, Y. N. Hou, S. Wang, S. Cao, Z. Y. Zhao, X. J. Xie, Y. Du, C. Lee, H. C. Lee, H. Zhang, Y. J. Zhao

The paper develops fluorescent probes to visualize SARM1 activation and identifies a nisoldipine derivative as a SARM1 inhibitor that protects axons from degeneration.

bioRxiv · Feb 24, 2021Biochemistry