Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer
F. Uhlitz, P. Bischoff, S. Peidli, A. Sieber, B. Obermayer, E. Blanc, A. Trinks, M. Luethen, Y. Ruchiy, T. Sell, S. Mamlouk, R. Arsie, T.-T. Wei, K. Klotz-Noack, R. Schwarz, , M. Morkel
The paper identifies mitogen-activated protein kinase activity as a driver of cell trajectories in colorectal cancer using single-cell transcriptomics and organoid models.
bioRxiv · Jan 10, 2020Cancer Biology