Author

T. Sell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:organoid / primary culture· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. Morkel· 3 shared C. Sers· 2 shared F. Uhlitz· 2 shared M. Luethen· 2 shared N. Bluthgen· 2 shared A. Sieber· 1 shared A. Trinks· 1 shared B. Fauler· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

M. Morkel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Oncogenic signalling is coupled to colorectal cancer cell differentiation state

T. Sell, C. Klotz, M. M. Fischer, R. Astaburuaga-Garciia, S. Krug, J. Drost, H. Clevers, M. Morkel, N. Bluthgen

This study shows oncogenic signalling in colorectal cancer is linked to cell differentiation states through a defined axis, with mutations affecting stemness and differentiation.

bioRxiv · Apr 7, 2022 · PreprintCancer Biology

Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer

F. Uhlitz, P. Bischoff, S. Peidli, A. Sieber, B. Obermayer, E. Blanc, A. Trinks, M. Luethen, Y. Ruchiy, T. Sell, S. Mamlouk, R. Arsie, T.-T. Wei, K. Klotz-Noack, R. Schwarz, , M. Morkel

The paper identifies mitogen-activated protein kinase activity as a driver of cell trajectories in colorectal cancer using single-cell transcriptomics and organoid models.

bioRxiv · Jan 10, 2020Cancer Biology

Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

R. Brandt, T. Sell, M. Luethen, F. Uhlitz, B. Klinger, P. Riemer, C. Giesecke, S. Schulze, I. A. El-Shimy, D. Kunkel, B. Fauler, T. Mielke, N. Mages, B. G. Herrmann, C. Sers, , M. Morkel

The paper investigates how oncogenic KRAS and BRAF differentially activate ERK in colon cancer and intestinal epithelium, revealing cell type-specific effects and novel regulatory mechanisms.

bioRxiv · Feb 14, 2019Cell Biology