Author

S. Peidli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

M. Landthaler· 3 shared A. D. Gruber· 2 shared A. Trinks· 2 shared A. Voss· 2 shared B. Obermayer· 2 shared C. Goffinet· 2 shared C. Sers· 2 shared D. Beule· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

M. Landthaler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

High-confidence calling of normal epithelial cells allows identification of a novel stem-like cell state in the colorectal cancer microenvironment

T.-T. Wei, E. Blanc, S. Peidli, P. Bischoff, A. Trinks, D. Horst, C. Sers, N. Bluthgen, D. Beule, M. Morkel, B. Obermayer

The paper develops CCISM to distinguish cancer cells from normal epithelial cells in single-cell data, identifying a novel stem-like cell state in the colorectal cancer microenvironment.

bioRxiv · Feb 23, 2024Cancer Biology

Single-cell-resolved interspecies comparison identifies a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19

S. Peidli, G. Nouailles, E. Wyler, J. M. Adler, S. Kunder, A. Voss, J. Kazmierski, F. Pott, P. Pennitz, D. Postmus, L. G. Teixeira Alves, C. Goffinet, A. D. Gruber, N. Bluethgen, M. Witzenrath, , S. D. Praktiknjo

The paper compares single-cell RNA-seq data from hamster and human COVID-19 samples to identify a shared inflammatory axis and a neutrophil-endothelial program associated with severe disease.

bioRxiv · Aug 25, 2023Immunology

A live attenuated vaccine confers superior mucosal and systemic immunity to SARS-CoV-2 variants

G. Nouailles, J. M. Adler, P. Pennitz, S. Peidli, G. Teixeira Alves, M. Baumgart, J. Bushe, A. Voss, A. Langenhagen, F. Pott, J. Kazmierski, C. Goekeri, S. Simmons, N. Xing, C. Langner, , J. Trimpert

This study compares immune responses and efficacy of different SARS-CoV-2 vaccines in hamsters, finding that a live-attenuated vaccine provides superior protection against variants.

bioRxiv · May 16, 2022Immunology

Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer

F. Uhlitz, P. Bischoff, S. Peidli, A. Sieber, B. Obermayer, E. Blanc, A. Trinks, M. Luethen, Y. Ruchiy, T. Sell, S. Mamlouk, R. Arsie, T.-T. Wei, K. Klotz-Noack, R. Schwarz, , M. Morkel

The paper identifies mitogen-activated protein kinase activity as a driver of cell trajectories in colorectal cancer using single-cell transcriptomics and organoid models.

bioRxiv · Jan 10, 2020Cancer Biology