Author

Y. V. Serebrenik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

G. M. Burslem· 2 shared O. Shalem· 2 shared S. E. Sansbury· 2 shared D. Mani· 1 shared J. Henao-Mejia· 1 shared O. H. Shalem· 1 shared S. Santhosh-Kumar· 1 shared T. Lapidot· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

G. M. Burslem

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3 papers

Recent·Most cited

Cell BiologyMolecular CellPeer-reviewedMay 1, 2025

Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

S. E. Sansbury, Y. V. Serebrenik, T. Lapidot…·O. Shalem

The paper develops a method to map unfolded protein responses by tagging endogenous proteins and analyzing their localization and stress responses using single-cell RNA sequencing.

DOI 10.1016/j.molcel.2025.04.002

humanspatial transcriptomics

𝕏 PostBluesky

Cell BiologyCell GenomicsPeer-reviewedOct 1, 2024

Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

Y. V. Serebrenik, D. Mani, T. Maujean…·O. Shalem

This paper introduces a method to systematically discover effector proteins for induced proximity therapeutics by combining high-throughput endogenous protein tagging with small molecule-based recruitment.

DOI 10.1016/j.xgen.2024.100651

humanmouse

𝕏 PostBluesky

Cell BiologybioRxivSep 10, 2018

Scalable tagging of endogenous genes by homology-independent intron targeting

Y. V. Serebrenik, S. E. Sansbury, S. Santhosh-Kumar…·O. H. Shalem

This paper introduces a method for scalable gene tagging that avoids homology-directed repair by using intron targeting, enabling efficient and flexible gene modification.

DOI 10.1101/gr.246413.118

genetic perturbation / CRISPRgene regulatory network inference

𝕏 PostBluesky