Author

Y. Yuthavong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:plant (other)· 2 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Pengon· 3 shared N. Jupatanakul· 3 shared S. Kamchonwongpaisan· 3 shared C. Pethrak· 2 shared C. Uthaipibull· 2 shared N. Posayapisit· 2 shared A. Saeung· 1 shared J. Vanichtanankul· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMicrobiology

J. Pengon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

New insights into antimalarial chemopreventive activity of antifolates

C. Pethrak, N. Posayapisit, J. Pengon, N. Suwanakitti, A. Saeung, M. Shorum, K. Aupalee, K. Taai, Y. Yuthavong, S. Kamchonwongpaisan, N. Jupatanakul

This study investigates antifolate activity against hepatic malaria parasites, showing that P218 is effective against resistant strains and provides insights for improved chemoprevention.

bioRxiv · Aug 17, 2021Microbiology

Transgenic pyrimethamine resistant Plasmodium berghei as a model for in vivo anti-DHFR drug testing

P. Koonyosying, N. Jupatanakul, J. Vanichtanankul, T. Saeyang, C. Pethrak, J. Pengon, W. Tipsuwan, Y. Yuthavong, S. Kamchonwongpaisan, C. Uthaipibull

This study creates a transgenic Plasmodium berghei model with quadruple DHFR mutations to test antifolate drugs in vivo, showing P218's effectiveness against resistant parasites.

bioRxiv · Sep 30, 2020 · PreprintMicrobiology

Transgenic pyrimethamine-resistant P. falciparum reveals transmission blocking potency of P218, a novel antifolate

N. Posayapisit, J. Pengon, P. Prommana, M. Shoram, Y. Yuthavong, C. Uthaipibull, S. Kamchonwongpaisan, N. Jupatanakul

This study develops transgenic P. falciparum resistant to pyrimethamine but capable of gametocyte production and shows that P218 inhibits exflagellation more effectively than its erythrocytic stage effect.

bioRxiv · Sep 6, 2020Microbiology