N. Jupatanakul

Differential intra-host infection kinetics in Aedes aegypti underlie superior transmissibility of African relative to Asian Zika virus

This study compares intra-host infection kinetics of African and Asian Zika virus in Aedes aegypti, finding the African lineage replicates faster and spreads more efficiently.

New insights into antimalarial chemopreventive activity of antifolates

This study investigates antifolate activity against hepatic malaria parasites, showing that P218 is effective against resistant strains and provides insights for improved chemoprevention.

Transgenic pyrimethamine resistant Plasmodium berghei as a model for in vivo anti-DHFR drug testing

This study creates a transgenic Plasmodium berghei model with quadruple DHFR mutations to test antifolate drugs in vivo, showing P218's effectiveness against resistant parasites.

Transgenic pyrimethamine-resistant P. falciparum reveals transmission blocking potency of P218, a novel antifolate

This study develops transgenic P. falciparum resistant to pyrimethamine but capable of gametocyte production and shows that P218 inhibits exflagellation more effectively than its erythrocytic stage effect.

High transmissibility and fetal pathogenicity of recent Zika virus strains from the African lineage

This study compares transmissibility and pathogenicity of recent African and Asian Zika virus strains, finding African strains more transmissible, lethal, and capable of causing fetal death.

Serratia marcescens secretes proteases and chitinases with larvicidal activity against Anopheles dirus

This study identifies Serratia marcescens proteases and chitinases with larvicidal activity against Anopheles dirus, suggesting their potential as biocontrol agents.