Author

Y.-C. Kuo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. M. Dauki· 1 shared C. C. Coss· 1 shared C. Song· 1 shared C.-S. Chen· 1 shared H. J. Kwon· 1 shared H. Xie· 1 shared J. A. Benedict· 1 shared M. A. Phelps· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. M. Dauki

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3 papers

Recent·Most cited

The structural mechanism underlying the antithetic effect of homologous RND1 and RhoD GTPases in plexin regulation

Y. Shan, X. Zhang, C. Song, Y. Liu, P. Ke, Y.-C. Kuo, Y. Wang

This study uses molecular dynamics simulations to show how RND1 and RhoD GTPases differentially affect plexin dimerization through distinct membrane interactions.

eLife · Jun 11, 2021Peer-reviewedBiophysics

Mapping the Antibody Repertoires in Ferrets with Repeated Influenza A/H3 Infections: Is Original Antigenic Sin Really "Sinful"?

T. Einav, M. Kosikova, P. Radvak, Y.-C. Kuo, H. J. Kwon, H. Xie

This study uses a new computational tool to analyze antibody repertoires in ferrets after repeated influenza infections, finding that broadly neutralizing antibodies can emerge despite original antigenic sin.

bioRxiv · Oct 22, 2020Immunology

Overcoming Resistance to Anabolic Selective Androgen Receptor Modulator (SARM) Therapy in Experimental Cancer Cachexia with Histone Deacetylase Inhibitor AR-42

Y.-C. Tseng, S. G. Liva, A. M. Dauki, M. Sovic, S. E. Henderson, Y.-C. Kuo, J. A. Benedict, S. K. Kulp, M. Campbell, T. Bekaii-Saab, M. A. Phelps, C.-S. Chen, C. C. Coss

This study combines a SARM and HDAC inhibitor to improve anti-cachectic efficacy in a mouse model of cancer cachexia, showing significant improvements in bodyweight and muscle mass.

bioRxiv · Oct 5, 2018 · PreprintCancer Biology