Author

Y.-C. Tseng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:ecology & biodiversity· 1 Organism:multiple species· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. M. Dauki· 1 shared C. C. Coss· 1 shared C.-C. Lin· 1 shared C.-I. Chang· 1 shared C.-S. Chen· 1 shared C.-Y. Hsu· 1 shared D. Lecchini· 1 shared G. Li· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCancer Biology

A. M. Dauki

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Author profile →

4 papers

Recent·Most cited

Megacolonies: an alternative social organization in anemonefishes?

M. Mercader, J. Zwahlen, K. Hayashi, H. Takamiyagi, Y.-C. Tseng, H.-T. Nguyen, K. Asada, J. Sowinski, J. Rimer, D. Lecchini, V. Laudet

The paper describes the discovery of 'megacolonies' in anemonefishes, which exhibit a different social structure compared to typical colonies, with reduced size-based hierarchy and aggression.

bioRxiv · Nov 6, 2022 · PreprintEcology

Signatures of adaptive evolution during human to mink SARS CoV2 cross species transmission inform estimates of the COVID19 pandemic timing

J.-H. Tai, S.-M. Chaw, H.-Y. Sun, Y.-C. Tseng, G. Li, S.-Y. Chang, S.-H. Yeh, P.-J. Chen, H.-Y. Wang

The paper analyzes SARS-CoV-2 sequences from minks and humans to determine if adaptive evolution occurred before the pandemic, suggesting the virus may have circulated in humans for at least six months prior to the Wuhan outbreak.

bioRxiv · Sep 15, 2021 · PreprintEvolutionary Biology

Molecular insights into substrate recognition and discrimination by the N-terminal domain of Lon AAA+ protease

S.-R. Tzeng, Y.-C. Tseng, C.-C. Lin, C.-Y. Hsu, S.-J. Huang, Y.-T. Kuo, C.-I. Chang

This study investigates how the N-terminal domain of Lon AAA+ protease recognizes and discriminates substrates through hydrophobic patches and flexible linkers.

eLife · Apr 30, 2021Peer-reviewedBiochemistry

Overcoming Resistance to Anabolic Selective Androgen Receptor Modulator (SARM) Therapy in Experimental Cancer Cachexia with Histone Deacetylase Inhibitor AR-42

Y.-C. Tseng, S. G. Liva, A. M. Dauki, M. Sovic, S. E. Henderson, Y.-C. Kuo, J. A. Benedict, S. K. Kulp, M. Campbell, T. Bekaii-Saab, M. A. Phelps, C.-S. Chen, C. C. Coss

This study combines a SARM and HDAC inhibitor to improve anti-cachectic efficacy in a mouse model of cancer cachexia, showing significant improvements in bodyweight and muscle mass.

bioRxiv · Oct 5, 2018 · PreprintCancer Biology