Author

Y.-Y. Kuo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Research Focus:cancer & tumor microenvironment· 4 Research Focus:cell type annotation· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:differential expression· 3 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C.-Y. Chao· 5 shared W.-T. Chen· 5 shared G.-B. Lin· 4 shared C.-H. Lu· 3 shared H.-H. Liu· 2 shared Y.-M. Chen· 2 shared A. ElSheikh· 1 shared C. M. Driggers· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersCancer Biology

C.-Y. Chao

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface

C. M. Driggers, Y.-Y. Kuo, P. Zhu, A. ElSheikh, S.-L. Shyng

This study reports the cryoEM structure of an open KATP channel with PIP2 bound, revealing two PIP2 binding sites and their role in channel regulation and neonatal diabetes.

bioRxiv · Aug 1, 2023 · PreprintBiochemistry

Thermal cycling-hyperthermia down-regulates liposaccharide-induced inflammation in human blood and helps with clearance of herpes simplex virus type 1

Y.-Y. Kuo, G.-B. Lin, W.-T. Chen, Y.-M. Chen, H.-H. Liu, C.-Y. Chao

The paper evaluates thermal cycling-hyperthermia (TC-HT) and finds it reduces LPS-induced inflammation and enhances HSV-1 clearance by macrophages compared to standard hyperthermia.

bioRxiv · Dec 20, 2022 · PreprintImmunology

Thermal cycling hyperthermia sensitizes non-small cell lung cancer A549 cells to EGFR-tyrosine kinase inhibitor Erlotinib

G.-B. Lin, W.-T. Chen, Y.-Y. Kuo, H.-H. Liu, Y.-M. Chen, S.-J. Leu, C.-Y. Chao

This study shows that thermal cycling hyperthermia enhances the effectiveness of Erlotinib in A549 NSCLC cells by reducing IC50 and inducing cell cycle arrest.

bioRxiv · May 3, 2022Cancer Biology

Study on the effect of a triple cancer treatment of propolis, thermal cycling-hyperthermia, and low-intensity ultrasound on PANC-1 cells

Y.-Y. Kuo, W.-T. Chen, G.-B. Lin, C.-H. Lu, C.-Y. Chao

This study evaluates a triple treatment combining propolis, thermal cycling-hyperthermia, and low-intensity ultrasound on PANC-1 cells, showing reduced viability and increased apoptosis through ROS accumulation and MAPK pathway activation.

bioRxiv · Nov 19, 2021 · PreprintCancer Biology

Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells

C.-H. Lu, Y.-Y. Kuo, G.-B. Lin, W.-T. Chen, C.-Y. Chao

This study combines chlorogenic acid, thermal-cycling hyperthermia, and low-intensity pulsed electric field to enhance anticancer effects on PANC-1 cells by inducing apoptosis and cell cycle arrest.

bioRxiv · Aug 23, 2019Cancer Biology

Thermal cycling-hyperthermia in combination with polyphenols, epigallocatechin gallate and chlorogenic acid, exerts synergistic anticancer effect against human pancreatic cancer PANC-1 cells

C.-H. Lu, W.-T. Chen, C.-H. Hsieh, Y.-Y. Kuo, C.-Y. Chao

This study shows that combining thermal cycling-hyperthermia with polyphenols EGCG and CGA synergistically kills pancreatic cancer cells by inducing cell cycle arrest and apoptosis.

bioRxiv · May 19, 2019Cancer Biology