MRGPRX4 is a novel bile acid receptor in cholestatic itch
Huasheng Yu, Tianjun Zhao, Simin Liu, Qinxue Wu, Omar Johnson, Zhaofa Wu, Zihao Zhuang, Yaocheng Shi, Luxin Peng, Renxi He, Yong Yang, Jianjun Sun, Xiaoqun Wang, Haifeng Xu, Zheng Zeng, , Yulong Li
The paper identifies MRGPRX4 as a novel bile acid receptor involved in cholestatic itch, showing its activation by bile acids and its role in itch induction in humans.
eLife · Sep 9, 2019Peer-reviewedNeuroscience