C9orf72 ALS-causing mutations lead to nucleoporin Nup107 aggregation and subsequent pathological changes
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, David Vı́lchez
This study shows C9orf72 ALS mutations cause Nup107 aggregation in motor neurons, leading to pathological changes and reduced lifespan in worm models.
bioRxiv · Apr 16, 2025 · PreprintCell Biology