Author

Yeonee Seol

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:virus· 1

Frequent Co-Authors

Anthony Maxwell· 1 shared Gabor Harami· 1 shared Ian L. MorganiD· 1 shared Jing Xu· 1 shared Jonathan E. SilveriD· 1 shared Keir C. Neuman· 1 shared Keir Cajal NeumaniD· 1 shared Mihir PrajapatiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Anthony Maxwell

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2 papers

Recent·Most cited

Type II topoisomerase substrate geometry revealed through combined experiment and computation.

Mihir Prajapati, Yeonee Seol, Jonathan E. Silver, Parth Rakesh Desai, Siddhartha Das, Keir Cajal Neuman

This study determines the 3D geometry of DNA crossings preferred for strand passage by topo II enzymes using single-molecule experiments and simulations.

bioRxiv · Sep 8, 2026 · PreprintBiophysics

Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq

Ian L. Morgan, Shannon J. McKie, Rachel Kim, Yeonee Seol, Jing Xu, Gabor Harami, Anthony Maxwell, Keir C. Neuman

This study develops SHAN-seq to map type II topoisomerase cleavage sites on DNA with high sensitivity, revealing hundreds of sites and enzyme-specific variations.

bioRxiv · May 17, 2024 · PreprintBiochemistry