Author

Ian L. Morgan

National Institutes of HealthORCID 0000-0001-6772-6883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:E. coli· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Keir Cajal NeumaniD· 2 shared Anthony MaxwelliD· 1 shared Gábor M. HaramiiD· 1 shared Jeffrey JianiD· 1 shared Jillian F ArmeniaiD· 1 shared Jing XuiD· 1 shared Neil OsheroffiD· 1 shared Rachel KimiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Keir Cajal NeumanORCID

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2 papers

Recent·Most cited

BiochemistryNucleic Acids ResearchPeer-reviewedMay 14, 2026

Bacterial type II topoisomerases cleave DNA in a species-specific manner

Ian L. Morgan, Jeffrey Jian, Jillian F Armenia…·Keir Cajal Neuman

The paper maps DNA cleavage sites of type II topoisomerases in three bacterial species, showing species-specific and drug-induced differences in cleavage specificity.

DOI 10.1093/nar/gkag527

E. colibacteria (other)

𝕏 PostBluesky

BiochemistryNucleic Acids ResearchPeer-reviewedAug 6, 2024

Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq

Ian L. Morgan, Shannon J. McKie, Rachel Kim…·Keir Cajal Neuman

This study develops SHAN-seq to map type II topoisomerase cleavage sites on DNA with high sensitivity, revealing hundreds of sites and enzyme-specific variations.

5 citations

E. coliDNA methylation

𝕏 PostBluesky