Author

Yi-Hua Jan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Michael HsiaoiD· 2 shared Bo-Hung Chen· 1 shared Cheng-Wen Wu· 1 shared Chi-Ying Huang· 1 shared Chih-Jen Yang· 1 shared Chiung-Fang Hsu· 1 shared Chun-Ming Cheng· 1 shared Erh-Hsuan Lin· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Michael HsiaoORCID

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2 papers

Recent·Most cited

Targeting BMI1 and MCL1 for Lung Adenocarcinoma Treatment

Erh-Hsuan Lin, Chiung-Fang Hsu, Yi-Hua Jan, Tsung-Hsien Lin, Hsiang-Yi Chang, Chun-Ming Cheng, Hui-Jan Hsu, Wei-Wei Chen, Bo-Hung Chen, Hsing-Fang Tsai, Jung-Jung Li, Chi-Ying Huang, Shih-Hsien Chuang, Jia-Ming Chang, Michael Hsiao, Cheng-Wen Wu

This study identifies BMI1 and MCL1 as key drivers of lung adenocarcinoma progression and demonstrates that targeting these proteins with a novel small-molecule inhibitor suppresses tumor growth in preclinical models.

bioRxiv · Oct 22, 2018 · PreprintCancer Biology

Adenylate kinase-4 modulates oxidative stress and stabilizes HIF-1α to drive lung cancer metastasis

Yi-Hua Jan, Tsung-Ching Lai, Chih-Jen Yang, Yuan-Feng Lin, Ming-Shyan Huang, Michael Hsiao

This study identifies AK4 as a driver of lung cancer metastasis by modulating oxidative stress and stabilizing HIF-1α, with potential therapeutic targeting of the AK4-HIF-1 axis.

bioRxiv · Oct 1, 2017 · PreprintCancer Biology