Author

Tsung-Hsien Lin

Kaohsiung Medical UniversityPrimary ORCID profile (0000-0002-5825-1254 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Tsung-Hsien LiniD1 paper · National Taiwan Ocean University

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Bo-Hung Chen· 1 shared Cai‐Mei ZhengiD· 1 shared Cathy S.J. FanniD· 1 shared Chang‐Hsun HsiehiD· 1 shared Cheng-Che Eric LaniD· 1 shared Cheng-Wen Wu· 1 shared Chi-Chin Sun· 1 shared Chi-Ying Huang· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Bo-Hung Chen

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Deleterious Variants Contribute Minimal Excess Risk in Large-Scale Testing

Yen‐Tsung Huang, En‐Yu Lai, Jia-Ying Su, Hsueh-Ju Lu, Yen‐Lin Chen, Jer-Yuarn Wu, Chunyu Wei, Ling‐Hui Li, Cathy S.J. Fann, Hsin‐Chou Yang, Chien-Hsiun Chen, Hung‐Hsin Chen, Yi-Min Liu, Ming-Fang Tsai, Erh‐Chan Yeh, , Chang‐Hsun Hsieh

The paper analyzes 292 disease-relevant deleterious variants in 486,956 participants to assess their risk differences, finding most have minimal impact.

medRxiv · Oct 21, 2024 · PreprintGenetic & Genomic Medicine

Targeting BMI1 and MCL1 for Lung Adenocarcinoma Treatment

Erh-Hsuan Lin, Chiung-Fang Hsu, Yi-Hua Jan, Tsung-Hsien Lin, Hsiang-Yi Chang, Chun-Ming Cheng, Hui-Jan Hsu, Wei-Wei Chen, Bo-Hung Chen, Hsing-Fang Tsai, Jung-Jung Li, Chi-Ying Huang, Shih-Hsien Chuang, Jia-Ming Chang, Michael Hsiao, Cheng-Wen Wu

This study identifies BMI1 and MCL1 as key drivers of lung adenocarcinoma progression and demonstrates that targeting these proteins with a novel small-molecule inhibitor suppresses tumor growth in preclinical models.

bioRxiv · Oct 22, 2018 · PreprintCancer Biology