Author

Binqian Zou

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Jun HeiD· 3 shared Chi Wang· 2 shared Chuanying Niu· 2 shared Dajiang QiniD· 2 shared Duanqing PeiiD· 2 shared He Li· 2 shared Xiaodong HuangiD· 2 shared Xiaoli XiongiD· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Jun HeORCID

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Author profile →

4 papers

Recent·Most cited

Enhanced Target Binding by Leritrelvir Restores Dimerization of Mpro Mutants and Mitigates Drug Resistance

Xiaodong Huang, Petr Kuzmič, S Zhang, Carlos A. Ramos‐Guzmán, Xiaoxin Chen, Jiacheng Gui, Qi Li, Shujuan Yan, Binqian Zou, Chuanying Niu, Y ZHAO, Haopeng Lin, Nannan Wang, Jiaheng Chen, Xinwen Chen, , Xiaoli Xiong

This study evaluates leritrelvir's effectiveness against Mpro variants with resistance mutations, showing it restores dimerization and maintains inhibitory activity better than nirmatrelvir.

bioRxiv · Jun 10, 2026 · PreprintMolecular Biology

Chromatin context-dependent deacetylation by the asymmetric Rpd3L

Hongyun Zhao, Huadong Li, Chi Wang, Xuechen Yang, He Li, Binqian Zou, Shuqi Dong, Nan Zhang, Yuxing Zhou, Li Yi, Ying Zhang, Yixuan Xie, Dajiang Qin, William Chong Hang Chao, Duanqing Pei, Jun He

This study reveals how the Rpd3L complex uses an asymmetric architecture to activate deacetylation in response to chromatin context.

Nucleic Acids Research · Apr 28, 2026Peer-reviewedMolecular Biology

Structural determinants of IGHV1-69 public antibodies conferring resilience to SARS-CoV-2 antigenic escape

Chuanying Niu, Xiaohan Huang, Qihong Yan, Banghui Liu, Xijie Gao, Yidong Song, J. Y. Wang, Longyu Wang, Zimu Li, Huiran Zheng, Ping He, Xiaodong Huang, Hang Yuan, Binqian Zou, Yuedong Yang, , Xiaoli Xiong

This study identifies structural features of affinity-matured R1-32-like antibodies that enable tolerance to SARS-CoV-2 mutations and reveals an ultrapotent antibody with broad variant activity.

bioRxiv · Mar 23, 2026 · PreprintImmunology

Structural basis for BCL7B-mediated ncBAF-nucleosome engagement

Fahui Sun, Binqian Zou, He Li, Chunqiang Xu, Qiaohong Luo, Chi Wang, Pengqi Xu, Duanqing Pei, JieKai CHEN, Dajiang Qin, Ying Zhang, Jun He

This study resolves the structural mechanism of ncBAF-nucleosome interaction, showing BCL7B's role in chromatin remodeling and its connection to nuclear actin networks.

Nucleic Acids Research · Jan 29, 2026Peer-reviewedMolecular Biology