Author

Yike Sun

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anastasia SacharidouiD· 1 shared Andrew S. LemoffiD· 1 shared Chieko MineoiD· 1 shared Kenian CheniD· 1 shared Lin Xu· 1 shared Philip W. ShauliD· 1 shared Shiva KeshavaiD· 1 shared Vijaya Mohan Rao· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPathology

Anastasia SacharidouORCID

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1 paper

Recent·Most cited

ApoE4 Promotes Thrombosis via Endothelial Cell ApoER2 and PP2A Activation

Yike Sun, Anastasia Sacharidou, Kenian Chen, Andrew S. Lemoff, Shiva Keshava, Vijaya Mohan Rao, Lin Xu, Chieko Mineo, Philip W. Shaul

This study identifies APOE4 as a risk factor for thrombosis by promoting vWF secretion through ApoER2 and PP2A activation in endothelial cells, leading to increased thrombosis in mice and human veins.

bioRxiv · Aug 21, 2026 · PreprintPathology