Author

Shiva Keshava

The University of Texas at TylerORCID 0000-0002-1760-6186Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anastasia SacharidouiD· 1 shared Andrew S. LemoffiD· 1 shared Chieko MineoiD· 1 shared Kenian CheniD· 1 shared Lin Xu· 1 shared Philip W. ShauliD· 1 shared Vijaya Mohan Rao· 1 shared Yike Sun· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPathology

Anastasia SacharidouORCID

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1 paper

Recent·Most cited

PathologybioRxivPreprintAug 21, 2026

ApoE4 Promotes Thrombosis via Endothelial Cell ApoER2 and PP2A Activation

Yike Sun, Anastasia Sacharidou, Kenian Chen…·Philip W. Shaul

This study identifies APOE4 as a risk factor for thrombosis by promoting vWF secretion through ApoER2 and PP2A activation in endothelial cells, leading to increased thrombosis in mice and human veins.

DOI 10.64898/2026.08.17.745317

mouseproteomics

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