Author

Yilin Ye

Macao Polytechnic University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Guiqin SuniD· 2 shared Jingjing GuoiD· 2 shared Qiange Lin· 2 shared Shaoxian Lyu· 2 shared Xinrong Lu· 2 shared Cuiying CheniD· 1 shared Guoliang ZhuiD· 1 shared Hongliang DuaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

Guiqin SunORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MINT: Predicting Enzyme-Cofactor Specificity by Multimodal Knowledge Transfer from Protein-Ligand Interactions

Yilin Ye, Xinkang Li, Hongliang Duan, Yingfeng An, Jingjing Guo

MINT predicts enzyme-cofactor specificity using a multimodal framework with transfer learning, achieving high accuracy in cofactor binding prediction.

bioRxiv · Oct 9, 2026 · PreprintBioengineering

Identification and characterization of emNagⅡ, a novel β-1,2-N-acetylglucosaminidase from Elizabethkingia meningoseptica

Shaoxian Lyu, Yongliang Tong, Qiange Lin, Yilin Ye, Xinliu Geng, Cuiying Chen, Xinrong Lu, Guiqin Sun, Li Chen

This paper identifies and characterizes emNagⅡ, a β-1,2-N-acetylglucosaminidase from Elizabethkingia meningoseptica that removes β-1,2-linked N-acetylglucosamine from living cell surfaces.

bioRxiv · Oct 15, 2025 · PreprintBiophysics

Identification and characterization of a novel exo-(N-)glycanase activity of NGLY1 on ENGase-digested N-GlcNAc proteins in vitro

Yilin Ye, Xinrong Lu, Shaoxian Lyu, Yuxin Zhang, Qiange Lin, Xin Qian, Junyou Lin, Zhijian Yu, Li Chen, Guiqin Sun

This study identifies and characterizes a novel exo-(N-)glycanase activity of NGLY1 on N-GlcNAc proteins in vitro, expanding its functional repertoire and linking it to clinical features of NGLY1-CDDG.

bioRxiv · Aug 21, 2025 · PreprintBiochemistry

ThermoLink: Bridging Disulfide Bond and EnzymeThermostability through Database Construction andMachine Learning Prediction

Ran Xu, Qican Pan, Guoliang Zhu, Yilin Ye, Minghui Xin, Zechen Wang, Sheng Wang, Weifeng Li, Yanjie Wei, Jingjing Guo, Liangzhen Zheng

The paper curates a database of disulfide bonds and their effects on protein thermostability, develops machine learning models to predict beneficial disulfide bonds, and demonstrates the utility of AlphaFold2 for this task.

Protein Science · Aug 15, 2024Peer-reviewedBioinformatics