Author

Xinrong Lu

Shanghai Medical College of Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1

Frequent Co-Authors

Shaoxian Lyu· 4 shared Cuiying CheniD· 3 shared Guiqin SuniD· 3 shared Yongliang TongiD· 3 shared Qiange Lin· 2 shared Yilin Ye· 2 shared Danfeng SheniD· 1 shared Gui-qin Sun· 1 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersBiochemistry

Shaoxian Lyu

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Author profile →

4 papers

Recent·Most cited

Identification and characterization of emNagⅡ, a novel β-1,2-N-acetylglucosaminidase from Elizabethkingia meningoseptica

Shaoxian Lyu, Yongliang Tong, Qiange Lin, Yilin Ye, Xinliu Geng, Cuiying Chen, Xinrong Lu, Guiqin Sun, Li Chen

This paper identifies and characterizes emNagⅡ, a β-1,2-N-acetylglucosaminidase from Elizabethkingia meningoseptica that removes β-1,2-linked N-acetylglucosamine from living cell surfaces.

bioRxiv · Oct 15, 2025 · PreprintBiophysics

Identification and characterization of a novel exo-(N-)glycanase activity of NGLY1 on ENGase-digested N-GlcNAc proteins in vitro

Yilin Ye, Xinrong Lu, Shaoxian Lyu, Yuxin Zhang, Qiange Lin, Xin Qian, Junyou Lin, Zhijian Yu, Li Chen, Guiqin Sun

This study identifies and characterizes a novel exo-(N-)glycanase activity of NGLY1 on N-GlcNAc proteins in vitro, expanding its functional repertoire and linking it to clinical features of NGLY1-CDDG.

bioRxiv · Aug 21, 2025 · PreprintBiochemistry

Down regulation of Engase in Caenorhabditis elegans may improve its stresses adaptivity

Xinrong Lu, Yongliang Tong, Mengting Wu, Shaoxian Lyu, Jiale Fan, Junyu Zheng, Lin Zou, Danfeng Shen, Lin Rao, Linlin Hou, Cuiying Chen, Xunjia Cheng, Guiqin Sun, Zhiyong Shao, Li Chen

This study shows that downregulating CeEngase in C. elegans enhances its adaptability to heat and osmotic stress.

Cells Tissues Organs · May 10, 2025Peer-reviewedBiochemistry

A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by affecting tumor associated macrophages

Yongliang Tong, Runqiu Chen, Xinrong Lu, Cuiying Chen, Gui-qin Sun, Xiaolu Yu, Shaoxian Lyu, Meiqing Feng, Yiru Long, Likun Gong, Li Chen

This study develops a nanobody-enzyme fusion protein targeting PD-L1 and sialic acid, showing anti-tumor effects by modulating tumor-associated macrophages.

International Journal of Biological Macromolecules · Jan 15, 2025Peer-reviewedPharmacology & Toxicology