Chronic fluoxetine treatment desensitizes serotoninergic inhibition of GABA inputs and the intrinsic excitability of dorsal raphe serotonin neurons
Wei Zhang, Ying Jin, Fu-Ming Zhou
This study shows that chronic fluoxetine treatment reduces serotoninergic inhibition of GABA inputs and intrinsic excitability of dorsal raphe serotonin neurons, potentially contributing to its antidepressant effects.
bioRxiv · May 7, 2024 · PreprintNeuroscience