Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation
Yingjie Hu, Victor A Lopez, Hengyi Xu, James P Pfister, Bing Song, Kelly A. Servage, Masahiro Sakurai, Benjamin T Jones, Joshua T. Mendell, Tao Wang, Jun Wu, Alan M Lambowitz, Diana R. Tomchick, Krzysztof Pawłowski, Vincent S. Tagliabracci
This study identifies C12orf29 as an RNA ligase that ligates tRNA and alters tRNA levels in mice, with structural insights into its catalytic mechanism.
Institutional Repositories DataBase (IRDB) · Oct 15, 2024Peer-reviewedBiochemistry