Vincent S. Tagliabracci

The paper reports an in vitro system of lipid kinases and phosphatases that self-organize into dynamic spatiotemporal patterns on model membranes.

This study identifies DUF4062 as TIR-like NADases involved in bacterial antiphage defense and eukaryotic RNA vault function through structural and biochemical analyses.

This paper introduces SidBait, a modular proximity ligation approach to identify small molecule and protein targets, validated with known interactions and applied to discover new targets like CaMKII and CapZ.

This study identifies ACAD10 as encoding two enzymes involved in ether lipid biosynthesis and salvage, linking them to type 2 diabetes risk.

The paper identifies NCI-2, a covalent inhibitor of the SARS-CoV-2 NiRAN domain, and presents a structural blueprint for drug design.

This study identifies C12orf29 as an RNA ligase that ligates tRNA and alters tRNA levels in mice, with structural insights into its catalytic mechanism.